N,N-Dimethylformamide CAS#68-12-2

N,N-Dimethylformamide CAS#68-12-2

Basic Information

Versatile Solvent:Dimethylformamide (DMF) dissolves in both water and organic solvents, making it highly adaptable for use across a variety of chemical processes.


Industrial Applications:Widely employed in the production of acrylic fibers, pharmaceuticals, dyes, petroleum products, and other organic chemicals.


Specialized Uses:Functions as a gasoline additive and is also utilized in electronics manufacturing, highlighting its utility in multiple technical fields.


Efficient Physical Properties:With a boiling point of 153°C, low freezing point of -61°C, and moderate vapor pressure, DMF is convenient for high-temperature reactions and industrial processes requiring stable liquid solvents.


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Products Description of N,N-Dimethylformamide CAS#68-12-2

N,N-Dimethylformamide (DMF) is a colorless, flammable liquid with a characteristic fishy odor. It has a molecular weight of 73.11, a boiling point of 153°C, a freezing point of -61°C, a flash point of 58°C, and a vapor pressure of 3 mmHg at 20°C. DMF is soluble in both water and a wide range of organic solvents. It presents hazards including flammability (explosive limits: LEL 2.2%, UEL 15.2%), toxicity, carcinogenicity, mutagenicity, and potential for skin irritation. It is extensively used as a solvent in the production of acrylic fibers, pharmaceuticals, dyes, petroleum products, and other organic chemicals, and also finds applications as a gasoline additive and in electronic manufacturing.


Product Application of N,N-Dimethylformamide CAS#68-12-2

N,N-Dimethylformamide (DMF) is primarily used as a solvent and extractant, especially for salts and high-molecular-weight compounds. Its versatility stems from a unique combination of physical and chemical properties, including low molecular mass, high dielectric constant, electron-donor capability, and complex-forming ability. Although its role as a reagent in chemical synthesis is less commercially significant, anhydrous DMF has been employed as a solvent in the preparation of cytotoxic luteinizing hormone-releasing hormone (LH-RH) conjugate AN-152 (a chemotherapeutic agent) and the fluorophore C625 [4-(N,N-diphenylamino)-4′-(6-O-hemiglutarate)hexylsulfinyl stilbene]. It also serves as a solvent medium in various organic reduction reactions.


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Parameters


Melting point-61 °C (lit.)
alpha0.94 º
Boiling point153 °C (lit.)
density0.944 g/mL (lit.)
vapor density2.5 (vs air)
vapor pressure2.7 mm Hg ( 20 °C)
refractive indexn20/D 1.430(lit.)
Fp136 °F
storage temp.Store at +5°C to +30°C.
solubilitywater: miscible
pka-0.44±0.70(Predicted)
formliquid
colorAPHA: ≤15
PH7 (200g/l, H2O, 20℃)
OdorFaint, ammonia-like odor detectable at 100 ppm
Relative polarity0.386
Odor Threshold1.8ppm
explosive limit2.2-16%(V)
Water Solubilitysoluble
λmaxλ: 270 nm Amax: 1.00
λ: 275 nm Amax: 0.30
λ: 295 nm Amax: 0.10
λ: 310 nm Amax: 0.05
λ: 340-400 nm Amax: 0.01
SensitiveHygroscopic
Merck143243
BRN605365
Exposure limitsNIOSH REL: TWA 10 ppm (30 mg/m3), IDLH 500 ppm; OSHA PEL: TWA 10 ppm; ACGIH TLV: TWA 10 ppm (adopted).
Dielectric constant36.71
InChIKeyZMXDDKWLCZADIW-UHFFFAOYSA-N
LogP-1.01
Surface tension35.20mN/m at 298.15K
Surface tension37.1mN/m at 20°C
CAS DataBase Reference68-12-2(CAS DataBase Reference)
NIST Chemistry ReferenceFormamide, N,N-dimethyl-(68-12-2)
IARC2A (Vol. 47, 71, 115) 2018
EPA Substance Registry SystemN,N-Dimethylformamide (68-12-2)


Safety Information


Hazard CodesT
Risk Statements61-20/21-36
Safety Statements53-45
RIDADRUN 2265 3/PG 3
OEBA
OELTWA: 10 ppm (30 mg/m3) [skin]
WGK Germany1
RTECSLQ2100000
F46091
Autoignition Temperature445 °C
Hazard NoteToxic
TSCAYes
HazardClass3
PackingGroupIII
HS Code29241990
Hazardous Substances Data68-12-2(Hazardous Substances Data)
ToxicityLD50 in mice, rats (ml/kg): 6.8, 7.6 orally; 6.2, 4.7 i.p. (Bartsch)
IDLA500 ppm



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FAQ

1. What kind of company is Bohai New Materials?
Bohai New Materials (Tianjin) Co., Ltd. is a foreign trade company specializing in the international trade of chemical products, located in the Binhai New Area of ​​Tianjin. Leveraging the strategic location of Tianjin Port, the company provides one-stop procurement and export services to global clients for a wide range of products, including plastic resins, basic chemical raw materials, fine chemicals, chemical fiber raw materials, and inorganic chemicals.


2. Which markets does the company serve?
Our products are primarily exported to Southeast Asia (Vietnam, Thailand, Indonesia, Malaysia), the Middle East (UAE, Saudi Arabia), Africa (Nigeria, Kenya), as well as Europe and the Americas.


3. Does the company have the qualifications to export hazardous chemicals?
Yes. We hold a valid license for the operation of hazardous chemicals and are well-versed in the export declaration, packaging, documentation, and transportation requirements for various types of hazardous goods. We are capable of handling the export of Class 3, Class 5, Class 8, and Class 9 hazardous chemicals.


4. What are the company's main products?
Our core product portfolio includes:
Plastic resins: PP, PE, PVC, ABS, PC, POM, etc.
Basic chemical raw materials: Soda ash, caustic soda, titanium dioxide, methanol, styrene, ethylene glycol, PTA, etc.
Fine chemicals: Pharmaceutical intermediates, pesticide intermediates, chemical additives, solvents, surfactants.
Chemical fiber raw materials: Polyester filament, polyester staple fiber, polyester chips (PET).
Inorganic chemicals: Calcium carbonate, talc powder, sodium sulfate, calcium chloride, magnesium chloride, etc.
Others: Paraffin wax, white oil, petroleum jelly (Vaseline), rubber, water treatment chemicals, etc.
If you have specific product requirements, please feel free to contact us; we will quickly source high-quality products to meet your needs.


5. How can I obtain a product quote? What information is required?
You can contact us via our official website, by phone, or by email. To ensure a quick and accurate quote, please provide the following details: product name and specifications, target purchase quantity, destination port, and desired delivery time. Please also inform us of any special packaging or testing requirements.

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