Silybin CAS#22888-70-6

Silybin CAS#22888-70-6

Basic Information

Primary Active Component of Silymarin:Represents 70–80% of the silymarin complex, ensuring high biological potency.


Strong Antioxidant and Anti:Inflammatory Activity – Effectively protects cells against oxidative stress and inflammation.


Broad Pharmacological Benefits:Exhibits anticancer, antidiabetic, antiviral, antimicrobial, and immunomodulatory properties.


Powerful Organ Protection:Provides significant hepatoprotective and neuroprotective effects.


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product description

Product Description of Silybin CAS#22888-70-6

Silybin, also referred to as silibinin, is the main biologically active component of the silymarin complex, accounting for approximately 70–80%, and consists of a mixture of silybin A and silybin B. Pharmacological studies have shown that silybin exhibits a wide range of biological activities, including strong antioxidant, anti-inflammatory, anticancer, antidiabetic, hepatoprotective, neuroprotective, antiviral, antimicrobial, and immunosuppressive effects.


Product Application of Silybin CAS#22888-70-6

Silibinin has been applied in various research studies, including:

Investigating its effects on the expression of genes related to chromatin regulation in prostate cancer using real-time polymerase chain reaction (RT-PCR).

Evaluating its influence on cell proliferation in platelet-derived growth factor (PDGF)–treated human Tenon’s fibroblasts (HTFs) by analyzing proliferating cell nuclear antigen (PCNA) expression and conducting water-soluble tetrazolium salt (WST-1) assays.

Examining its impact on the gene expression of stromelysin-1 (STM1), acetyl hexosamines, and collagen synthesis during the process of skin wound healing.

Studying its inhibitory activity against Escherichia coli ATP synthase.


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Product Information

Parameters


Melting point164-174°C
alphaD20 +11° (c = 0.25 in acetone + alcohol)
Boiling point793.0±60.0 °C(Predicted)
density1.527±0.06 g/cm3(Predicted)
storage temp.-20°C
solubilityAcetone (Sparingly), DMSO, Methano (Sparingly)
formSolid
pkapKa 6.42±0.04 (Uncertain)
colorPale Yellow
Water Solubility54mg/L(24.99 ºC)
Merck138607
Stability:Stable. Incompatible with strong oxidizing agents, strong bases.
LogP4.232 (est)
CAS DataBase22888-70-6(CAS DataBase Reference)
Reference
Hazard CodesXi
Risk Statements36/37/38
Safety Statements26-37/39-24/25-22-36
RIDADR3172
WGK Germany3
RTECSDJ2981770
HS Code29329990
ToxicityLD50 intravenous in mouse: 1056mg/kg


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FAQ

1. What kind of company is Bohai New Materials?
Bohai New Materials (Tianjin) Co., Ltd. is a foreign trade company specializing in the international trade of chemical products, located in the Binhai New Area of ​​Tianjin. Leveraging the strategic location of Tianjin Port, the company provides one-stop procurement and export services to global clients for a wide range of products, including plastic resins, basic chemical raw materials, fine chemicals, chemical fiber raw materials, and inorganic chemicals.


2. Which markets does the company serve?
Our products are primarily exported to Southeast Asia (Vietnam, Thailand, Indonesia, Malaysia), the Middle East (UAE, Saudi Arabia), Africa (Nigeria, Kenya), as well as Europe and the Americas.


3. Does the company have the qualifications to export hazardous chemicals?
Yes. We hold a valid license for the operation of hazardous chemicals and are well-versed in the export declaration, packaging, documentation, and transportation requirements for various types of hazardous goods. We are capable of handling the export of Class 3, Class 5, Class 8, and Class 9 hazardous chemicals.


4. What are the company's main products?
Our core product portfolio includes:
Plastic resins: PP, PE, PVC, ABS, PC, POM, etc.
Basic chemical raw materials: Soda ash, caustic soda, titanium dioxide, methanol, styrene, ethylene glycol, PTA, etc.
Fine chemicals: Pharmaceutical intermediates, pesticide intermediates, chemical additives, solvents, surfactants.
Chemical fiber raw materials: Polyester filament, polyester staple fiber, polyester chips (PET).
Inorganic chemicals: Calcium carbonate, talc powder, sodium sulfate, calcium chloride, magnesium chloride, etc.
Others: Paraffin wax, white oil, petroleum jelly (Vaseline), rubber, water treatment chemicals, etc.
If you have specific product requirements, please feel free to contact us; we will quickly source high-quality products to meet your needs.


5. How can I obtain a product quote? What information is required?
You can contact us via our official website, by phone, or by email. To ensure a quick and accurate quote, please provide the following details: product name and specifications, target purchase quantity, destination port, and desired delivery time. Please also inform us of any special packaging or testing requirements.

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