β-Estradiol CAS#50-28-2

β-Estradiol CAS#50-28-2

Basic Information

Key Natural Estrogen Hormone: Estradiol is the most important and biologically active estrogen in the human body.


Naturally Derived Steroid Hormone: Primarily secreted by ovarian follicles, corpus luteum, and the placenta during pregnancy.


High Biological Activity: Exhibits strong physiological activity among all estrogen hormones.


Essential Role in Reproductive Health: Plays a central role in regulating female reproductive endocrine functions.



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product description

Product Description of β-Estradiol CAS#50-28-2

Estradiol is a steroid hormone primarily secreted by ovarian follicles, the corpus luteum, and the placenta during pregnancy. It is the most important and biologically active hormone among estrogens.


Product Application of β-Estradiol CAS#50-28-2

Estradiol, an estrogen drug, treats abnormal uterine bleeding, primary amenorrhea, menopause syndrome and prostate cancer. It regulates female genital development and secondary sexual features, and boosts mammary duct growth. High doses inhibit prolactin secretion to stop lactation.
It may cause nausea, vomiting and irregular bleeding. Caution is needed for liver and kidney dysfunction patients, and local genital use is prohibited.


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Product Information

Parameters


Melting point178-179 °C(lit.)
alphaD25 +76 to +83° (dioxane)
Boiling point355.44°C (rough estimate)
density1.0708 (rough estimate)
refractive index80.4 ° (C=1, Dioxane)
Fp2℃
storage temp.room temp
solubilityPractically insoluble in water, soluble in acetone, sparingly soluble in ethanol (96 per cent), slightly soluble in methylene chloride.
pkapKa 10.71±0.02(H2O(0.1% p-dioxane) t=25±0.1 I=0.03(KCl))(Approximate)
formpowder
colorWhite to off-white
biological sourcesynthetic (organic)
Water SolubilitySoluble in dimethyl sulfoxide, ethanol , water, phosphate buffer saline, dimethyl formamide, acetone, dioxane and alkali hydroxides. Slightly soluble in vegetable oils.
Merck143703
BRN1914275
BCS Class1
Stability:Stable. Incompatible with strong oxidizing agents.
InChIKeyVOXZDWNPVJITMN-ZBRFXRBCSA-N
CAS DataBase Reference50-28-2(CAS DataBase Reference)
NIST Chemistry ReferenceEstra-1,3,5(10)-triene-3,17beta-diol(50-28-2)
EPA Substance Registry SystemEstradiol (50-28-2)


Safety Information


Hazard CodesT,Xn,F
Risk Statements60-61-45-63-64-40-36-20/21/22-11-48
Safety Statements53-22-36/37/39-45-36/37-26-16-36-20
RIDADR2811
WGK Germany3
RTECSKG2975000
F45879
HazardClass6.1
PackingGroupIII
HS Code29372390
Hazardous Substances Data50-28-2(Hazardous Substances Data)
ToxicityLD50 subcutaneous in rat: > 300mg/kg


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FAQ

1. What kind of company is Bohai New Materials?
Bohai New Materials (Tianjin) Co., Ltd. is a foreign trade company specializing in the international trade of chemical products, located in the Binhai New Area of ​​Tianjin. Leveraging the strategic location of Tianjin Port, the company provides one-stop procurement and export services to global clients for a wide range of products, including plastic resins, basic chemical raw materials, fine chemicals, chemical fiber raw materials, and inorganic chemicals.


2. Which markets does the company serve?
Our products are primarily exported to Southeast Asia (Vietnam, Thailand, Indonesia, Malaysia), the Middle East (UAE, Saudi Arabia), Africa (Nigeria, Kenya), as well as Europe and the Americas.


3. Does the company have the qualifications to export hazardous chemicals?
Yes. We hold a valid license for the operation of hazardous chemicals and are well-versed in the export declaration, packaging, documentation, and transportation requirements for various types of hazardous goods. We are capable of handling the export of Class 3, Class 5, Class 8, and Class 9 hazardous chemicals.


4. What are the company's main products?
Our core product portfolio includes:
Plastic resins: PP, PE, PVC, ABS, PC, POM, etc.
Basic chemical raw materials: Soda ash, caustic soda, titanium dioxide, methanol, styrene, ethylene glycol, PTA, etc.
Fine chemicals: Pharmaceutical intermediates, pesticide intermediates, chemical additives, solvents, surfactants.
Chemical fiber raw materials: Polyester filament, polyester staple fiber, polyester chips (PET).
Inorganic chemicals: Calcium carbonate, talc powder, sodium sulfate, calcium chloride, magnesium chloride, etc.
Others: Paraffin wax, white oil, petroleum jelly (Vaseline), rubber, water treatment chemicals, etc.
If you have specific product requirements, please feel free to contact us; we will quickly source high-quality products to meet your needs.


5. How can I obtain a product quote? What information is required?
You can contact us via our official website, by phone, or by email. To ensure a quick and accurate quote, please provide the following details: product name and specifications, target purchase quantity, destination port, and desired delivery time. Please also inform us of any special packaging or testing requirements.

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