Progesterone CAS#57-83-0

Progesterone CAS#57-83-0

Basic Information

Natural Endogenous Progestogen Hormone:Progesterone is the body’s primary naturally occurring progestogen, secreted by the ovarian luteal cells, ensuring excellent biological relevance and compatibility.


Key Steroid Hormone IntermediateIt serves as an important intermediate for the synthesis of all steroid hormones, making it highly valuable in pharmaceutical and hormone-related applications.


Dual Crystal Forms with Identical ActivityAvailable in both α-type and β-type crystal forms, both providing the same physiological activity for flexible formulation use.


Excellent Solvent CompatibilityAlthough insoluble in water, progesterone is readily soluble in ethanol, ether, chloroform, acetone, dioxane, and concentrated sulfuric acid, supporting diverse processing and formulation requirements.



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product description

Products Description of Progesterone CAS#57-83-0

Progesterone is an endogenous steroid hormone mainly secreted by ovaries, acting as a major natural progestogen and key intermediate for steroid hormone synthesis.

It has two crystal forms with identical bioactivity. Insoluble in water, it dissolves readily in most organic solvents and concentrated sulfuric acid.


Product Application of Progesterone CAS#57-83-0

Progesterone cooperates with estrogen to transform endometrium for embryo implantation, maintains pregnancy by restraining uterine contraction, and facilitates breast development for lactation. High doses suppress ovulation via hormonal feedback.

It is clinically applied to treat threatened abortion, irregular bleeding, dysmenorrhea, amenorrhea and other gynecological disorders, as well as prostatic hyperplasia and related complications.


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Product Information

Parameters


Melting point128-132 °C (lit.)
alpha186 º (c=1, ethanol)
Boiling point394.13°C (rough estimate)
densityd23 1.166; d20 1.171
refractive index182 ° (C=2, Dioxane)
Fp2℃
storage temp.room temp
solubilityH2O: 25 mg/mL, may be clear to slightly hazy
formpowder
colorYellow to yellow-brown
biological sourcesynthetic (organic)
Water Solubility<0.1 g/100 mL at 19 ºC
Merck7773
BRN1915950
BCS Class4
Stability:Stable. Incompatible with strong oxidizing agents.
InChIKeyRJKFOVLPORLFTN-LEKSSAKUSA-N
LogP3.87
CAS DataBase Reference57-83-0(CAS DataBase Reference)
NIST Chemistry ReferenceProgesterone(57-83-0)
EPA Substance Registry SystemProgesterone (57-83-0)


Safety Information


Hazard CodesXn,T,F
Risk Statements40-45-62-36-20/21/22-11
Safety Statements36/37-45-53-16
RIDADRUN 1648 3 / PGII
WGK Germany3
RTECSTW0175000
HS Code29372390
Hazardous Substances Data57-83-0(Hazardous Substances Data)
ToxicityLD50 intraperitoneal in rat: 327mg/kg









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FAQ

1. What kind of company is Bohai New Materials?
Bohai New Materials (Tianjin) Co., Ltd. is a foreign trade company specializing in the international trade of chemical products, located in the Binhai New Area of ​​Tianjin. Leveraging the strategic location of Tianjin Port, the company provides one-stop procurement and export services to global clients for a wide range of products, including plastic resins, basic chemical raw materials, fine chemicals, chemical fiber raw materials, and inorganic chemicals.


2. Which markets does the company serve?
Our products are primarily exported to Southeast Asia (Vietnam, Thailand, Indonesia, Malaysia), the Middle East (UAE, Saudi Arabia), Africa (Nigeria, Kenya), as well as Europe and the Americas.


3. Does the company have the qualifications to export hazardous chemicals?
Yes. We hold a valid license for the operation of hazardous chemicals and are well-versed in the export declaration, packaging, documentation, and transportation requirements for various types of hazardous goods. We are capable of handling the export of Class 3, Class 5, Class 8, and Class 9 hazardous chemicals.


4. What are the company's main products?
Our core product portfolio includes:
Plastic resins: PP, PE, PVC, ABS, PC, POM, etc.
Basic chemical raw materials: Soda ash, caustic soda, titanium dioxide, methanol, styrene, ethylene glycol, PTA, etc.
Fine chemicals: Pharmaceutical intermediates, pesticide intermediates, chemical additives, solvents, surfactants.
Chemical fiber raw materials: Polyester filament, polyester staple fiber, polyester chips (PET).
Inorganic chemicals: Calcium carbonate, talc powder, sodium sulfate, calcium chloride, magnesium chloride, etc.
Others: Paraffin wax, white oil, petroleum jelly (Vaseline), rubber, water treatment chemicals, etc.
If you have specific product requirements, please feel free to contact us; we will quickly source high-quality products to meet your needs.


5. How can I obtain a product quote? What information is required?
You can contact us via our official website, by phone, or by email. To ensure a quick and accurate quote, please provide the following details: product name and specifications, target purchase quantity, destination port, and desired delivery time. Please also inform us of any special packaging or testing requirements.

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