Carbamazepine CAS#298-46-4

Carbamazepine CAS#298-46-4

Basic Information

Broad Antiepileptic Efficacy: Carbamazepine is effective in managing psychomotor seizures, grand mal seizures, localized seizures, and mixed seizure types, offering broad therapeutic coverage.


Superior Peripheral Neuropathy Support: Compared with phenytoin sodium, it provides better therapeutic performance in the treatment of peripheral neuropathy.


Effective Neuralgia Treatment: It is widely used for the management of trigeminal neuralgia and glossopharyngeal neuralgia, delivering reliable pain-relief benefits.


Versatile Clinical Applications: In addition to epilepsy treatment, carbamazepine can also be applied in arrhythmia and diabetes insipidus management, highlighting its multifunctional pharmaceutical value.


Can't Find The Product You Need?

Tell Us Your Product Requirements, Specifications And Target Industry, Our Professional Team Will Reply You Within 24 Hours.

Contact us

Products Center

product description

Product Description of Carbamazepine CAS#298-46-4

Carbamazepine is a white or pale crystalline dibenzazepine antiepileptic agent. It works similarly to phenytoin sodium and is highly effective against psychomotor, generalized and partial seizures.

It shows superior effects on peripheral neuropathy, and is commonly used to relieve trigeminal and glossopharyngeal neuralgia. It is also applicable for arrhythmia and diabetes insipidus with wide clinical uses.

Product Application of Carbamazepine CAS#298-46-4

Carbamazepine is a dibenzazepine antiepileptic with effects similar to phenytoin sodium. It mainly treats psychomotor, generalized and partial seizures, and works better than phenytoin sodium for peripheral neuropathy, trigeminal and glossopharyngeal neuralgia. It is also used for arrhythmia and diabetes insipidus.
Its oral LD50 is 3750 mg/kg in mice and 4025 mg/kg in rats. Pharmacologically, it acts as a sodium channel inhibitor and binds to GABAA receptor benzodiazepine sites for medical and research use.


Products Center

Product Information

Parameters


Melting point191-192 °C (lit.)
Boiling point378.73°C (rough estimate)
density1.1099 (rough estimate)
refractive index1.5906 (estimate)
Fp9℃
storage temp.2-8°C
solubility45% (w/v) aq 2-hydroxypropyl-β-cyclodextrin: soluble29mg/mL
formCrystals
pka13.94±0.20(Predicted)
colorAlmost white
Water Solubilitypract. insoluble
Merck141781
BCS Class2
LogP2.45
CAS DataBase Reference298-46-4(CAS DataBase Reference)
NIST Chemistry ReferenceCarbamazepine(298-46-4)
EPA Substance Registry System5H-Dibenz[b,f]azepine-5-carboxamide (298-46-4)


Safety Information


Hazard CodesXn,T,F
Risk Statements42/43-22-20/21/22-39/23/24/25-23/24/25-11
Safety Statements37-24-22-36/37/39-36-45-36/37-16
RIDADRUN1230 - class 3 - PG 2 - Methanol, solution
WGK Germany2
RTECSHN8225000
HS Code29339900
Hazardous Substances Data298-46-4(Hazardous Substances Data)
ToxicityLD50 orally in mice, rats: 3750, 4025 mg/kg (Stenger, Roulet)


Products Center

Factory Showcase

拼图_美图设计室-(1)

Products Center

Shipping And Transportation

拼图_美图设计室

Products Center

FAQ

1. What kind of company is Bohai New Materials?
Bohai New Materials (Tianjin) Co., Ltd. is a foreign trade company specializing in the international trade of chemical products, located in the Binhai New Area of ​​Tianjin. Leveraging the strategic location of Tianjin Port, the company provides one-stop procurement and export services to global clients for a wide range of products, including plastic resins, basic chemical raw materials, fine chemicals, chemical fiber raw materials, and inorganic chemicals.


2. Which markets does the company serve?
Our products are primarily exported to Southeast Asia (Vietnam, Thailand, Indonesia, Malaysia), the Middle East (UAE, Saudi Arabia), Africa (Nigeria, Kenya), as well as Europe and the Americas.


3. Does the company have the qualifications to export hazardous chemicals?
Yes. We hold a valid license for the operation of hazardous chemicals and are well-versed in the export declaration, packaging, documentation, and transportation requirements for various types of hazardous goods. We are capable of handling the export of Class 3, Class 5, Class 8, and Class 9 hazardous chemicals.


4. What are the company's main products?
Our core product portfolio includes:
Plastic resins: PP, PE, PVC, ABS, PC, POM, etc.
Basic chemical raw materials: Soda ash, caustic soda, titanium dioxide, methanol, styrene, ethylene glycol, PTA, etc.
Fine chemicals: Pharmaceutical intermediates, pesticide intermediates, chemical additives, solvents, surfactants.
Chemical fiber raw materials: Polyester filament, polyester staple fiber, polyester chips (PET).
Inorganic chemicals: Calcium carbonate, talc powder, sodium sulfate, calcium chloride, magnesium chloride, etc.
Others: Paraffin wax, white oil, petroleum jelly (Vaseline), rubber, water treatment chemicals, etc.
If you have specific product requirements, please feel free to contact us; we will quickly source high-quality products to meet your needs.


5. How can I obtain a product quote? What information is required?
You can contact us via our official website, by phone, or by email. To ensure a quick and accurate quote, please provide the following details: product name and specifications, target purchase quantity, destination port, and desired delivery time. Please also inform us of any special packaging or testing requirements.

Products Center

Contact Us

Submit

Products Center

Recommendation