Loratadine CAS#79794-75-5

Loratadine CAS#79794-75-5

Basic Information

Fast-acting and Long-lasting Relief:Loratadine provides rapid onset of action with prolonged antihistamine effects, ensuring sustained symptom control.


Non-sedating and Hormone-free:As a second-generation antihistamine, it does not contain hormones and has no significant central nervous system inhibitory effects.


Effective Allergy Symptom Control:It relieves symptoms of allergic rhinitis, such as sneezing, runny nose, and nasal itching, as well as eye irritation and skin allergies like urticaria.


Safe and Well-tolerated:Lacks significant anticholinergic effects, and toxicological studies show no mutagenic or teratogenic risks in animals.


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product description

Product Description of Loratadine CAS#79794-75-5

Loratadine is a second-generation long-acting tricyclic antihistamine for anti-allergy use. It acts fast powerfully without hormones, and is metabolized into more potent desloratadine in vivo.

It competitively blocks histamine H1 receptors to ease allergic symptoms, with few anticholinergic and sedative effects. It relieves allergic rhinitis and chronic urticaria symptoms. Animal tests prove it has no mutagenic or teratogenic risks.


Product Application of Loratadine CAS#79794-75-5

Loratadine is a highly selective antihistamine for peripheral H1 receptors, providing strong and long-lasting effects. It is used in the treatment of allergic conditions such as allergic rhinitis.

As a nationally classified Class II antiallergic drug, it is applied to relieve both nasal and non-nasal symptoms associated with seasonal allergic rhinitis, as well as to alleviate symptoms of chronic urticaria.


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Product Information

Parameters


Melting point134-136°C
Boiling point531.3±50.0 °C(Predicted)
density1.261±0.06 g/cm3(Predicted)
RTECSTM6129200
storage temp.2-8°C
solubilityDMSO: 26 mg/mL, soluble
formpowder
pka4.27±0.20(Predicted)
colorwhite
Water SolubilityIt is soluble in DMSO (50 mg/ml), ethanol (77 mg/ml at 25°C), water (<1 mg/ml at 25°C), chloroform, and methanol.
Merck145578
BCS Class2
Stability:Stable, but may be heat sensitive - refrigerate. Incompatible with strong oxidizing agents.
InChIKeyJCCNYMKQOSZNPW-UHFFFAOYSA-N
CAS DataBase Reference79794-75-5(CAS DataBase Reference)
EPA Substance Registry System1-Piperidinecarboxylic acid, 4-(8-chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-, ethyl ester (79794-75-5)
Hazard CodesXi
Risk Statements36/37/38
Safety Statements22-24/25-36-26
RIDADR3077
WGK Germany2
HS Code29333990
Hazardous Substances Data79794-75-5(Hazardous Substances Data)


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FAQ

1. What kind of company is Bohai New Materials?
Bohai New Materials (Tianjin) Co., Ltd. is a foreign trade company specializing in the international trade of chemical products, located in the Binhai New Area of ​​Tianjin. Leveraging the strategic location of Tianjin Port, the company provides one-stop procurement and export services to global clients for a wide range of products, including plastic resins, basic chemical raw materials, fine chemicals, chemical fiber raw materials, and inorganic chemicals.


2. Which markets does the company serve?
Our products are primarily exported to Southeast Asia (Vietnam, Thailand, Indonesia, Malaysia), the Middle East (UAE, Saudi Arabia), Africa (Nigeria, Kenya), as well as Europe and the Americas.


3. Does the company have the qualifications to export hazardous chemicals?
Yes. We hold a valid license for the operation of hazardous chemicals and are well-versed in the export declaration, packaging, documentation, and transportation requirements for various types of hazardous goods. We are capable of handling the export of Class 3, Class 5, Class 8, and Class 9 hazardous chemicals.


4. What are the company's main products?
Our core product portfolio includes:
Plastic resins: PP, PE, PVC, ABS, PC, POM, etc.
Basic chemical raw materials: Soda ash, caustic soda, titanium dioxide, methanol, styrene, ethylene glycol, PTA, etc.
Fine chemicals: Pharmaceutical intermediates, pesticide intermediates, chemical additives, solvents, surfactants.
Chemical fiber raw materials: Polyester filament, polyester staple fiber, polyester chips (PET).
Inorganic chemicals: Calcium carbonate, talc powder, sodium sulfate, calcium chloride, magnesium chloride, etc.
Others: Paraffin wax, white oil, petroleum jelly (Vaseline), rubber, water treatment chemicals, etc.
If you have specific product requirements, please feel free to contact us; we will quickly source high-quality products to meet your needs.


5. How can I obtain a product quote? What information is required?
You can contact us via our official website, by phone, or by email. To ensure a quick and accurate quote, please provide the following details: product name and specifications, target purchase quantity, destination port, and desired delivery time. Please also inform us of any special packaging or testing requirements.

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