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  • Metformin hydrochloride CAS#1115-70-4
  • Metformin hydrochloride CAS#1115-70-4
  • Metformin hydrochloride CAS#1115-70-4
  • Metformin hydrochloride CAS#1115-70-4
  • Metformin hydrochloride CAS#1115-70-4

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Metformin hydrochloride CAS#1115-70-4

Metformin hydrochloride CAS#1115-70-4

Basic Information

Effective Oral Hypoglycemic Agent: Metformin hydrochloride is a well-established biguanide oral hypoglycemic drug widely used for blood glucose management.


Promotes Glycogen Formation: It helps promote the conversion of glucose into glycogen, supporting better glucose utilization and storage.


Reduces Glucagon Secretion: The product works by reducing glucagon secretion from pancreatic A cells, which contributes to improved blood sugar control.


Non-Insulin Secretagogue Mechanism: A key advantage is that it does not stimulate pancreatic β-cells to secrete insulin, making its mechanism distinct and suitable for specific therapeutic applications.


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product description

Product Description of Metformin hydrochloride CAS#1115-70-4

Metformin hydrochloride is an oral biguanide hypoglycemic agent. Though less potent than phenformin, it can effectively regulate blood sugar.

It lowers blood glucose by inhibiting glucagon release and accelerating glycogen synthesis. It does not stimulate insulin secretion, hence ideal for non-insulin-dependent diabetic patients.


Product Application of Metformin hydrochloride CAS#1115-70-4

Metformin hydrochloride is an oral hypoglycemic agent widely used to manage type 2 diabetes. It effectively reduces fasting and postprandial blood glucose levels, and can lower HbA1c by 1% to 2%.


The primary mechanisms of action include

It boosts peripheral insulin sensitivity and glucose uptake, facilitates glucose consumption in insulin-independent tissues, suppresses hepatic gluconeogenesis and intestinal glucose absorption.
Indicated for mild type 2 diabetes. It exerts hypoglycemic effects and improves insulin sensitivity via the LKB1-AMPK signaling pathway.


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Product Information

Parameters


Melting point223-226 °C(lit.)
density1.36[at 20℃]
vapor pressure0.001Pa at 25℃
Fp9℃
storage temp.2-8°C
solubilityFreely soluble in water, slightly soluble in alcohol, practically insoluble in acetone and in methylene chloride
pka12.4[at 20 ℃]
formPowder
colorWhite
Water SolubilitySoluble in water (50 mg/ml), ethanol, and DMSO (50 mM).
λmax233nm(H2O)(lit.)
Merck145938
BCS Class3
Stability:Stable for 2 years from date of purchase as supplied. Solutions in DMSO or distilled water may be stored at -20° for up to 2 months.
InChIKeyOETHQSJEHLVLGH-UHFFFAOYSA-N
LogP-3.5 at 20℃
CAS DataBase Reference1115-70-4(CAS DataBase Reference)


Safety Information


Hazard CodesXn,T,F
Risk Statements22-36/38-39/23/24/25-23/24/25-11
Safety Statements26-36-45-36/37-16-7
RIDADRUN1230 - class 3 - PG 2 - Methanol, solution
WGK Germany3
RTECSDU1800000
HS Code29252900
Hazardous Substances Data1115-70-4(Hazardous Substances Data)
ToxicityLD50 in rats (mg/kg): 1000 orally, 300 s.c. (Rx Bulletin)


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FAQ

1. What kind of company is Bohai New Materials?
Bohai New Materials (Tianjin) Co., Ltd. is a foreign trade company specializing in the international trade of chemical products, located in the Binhai New Area of ​​Tianjin. Leveraging the strategic location of Tianjin Port, the company provides one-stop procurement and export services to global clients for a wide range of products, including plastic resins, basic chemical raw materials, fine chemicals, chemical fiber raw materials, and inorganic chemicals.


2. Which markets does the company serve?
Our products are primarily exported to Southeast Asia (Vietnam, Thailand, Indonesia, Malaysia), the Middle East (UAE, Saudi Arabia), Africa (Nigeria, Kenya), as well as Europe and the Americas.


3. Does the company have the qualifications to export hazardous chemicals?
Yes. We hold a valid license for the operation of hazardous chemicals and are well-versed in the export declaration, packaging, documentation, and transportation requirements for various types of hazardous goods. We are capable of handling the export of Class 3, Class 5, Class 8, and Class 9 hazardous chemicals.


4. What are the company's main products?
Our core product portfolio includes:
Plastic resins: PP, PE, PVC, ABS, PC, POM, etc.
Basic chemical raw materials: Soda ash, caustic soda, titanium dioxide, methanol, styrene, ethylene glycol, PTA, etc.
Fine chemicals: Pharmaceutical intermediates, pesticide intermediates, chemical additives, solvents, surfactants.
Chemical fiber raw materials: Polyester filament, polyester staple fiber, polyester chips (PET).
Inorganic chemicals: Calcium carbonate, talc powder, sodium sulfate, calcium chloride, magnesium chloride, etc.
Others: Paraffin wax, white oil, petroleum jelly (Vaseline), rubber, water treatment chemicals, etc.
If you have specific product requirements, please feel free to contact us; we will quickly source high-quality products to meet your needs.


5. How can I obtain a product quote? What information is required?
You can contact us via our official website, by phone, or by email. To ensure a quick and accurate quote, please provide the following details: product name and specifications, target purchase quantity, destination port, and desired delivery time. Please also inform us of any special packaging or testing requirements.

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