Metronidazole CAS#443-48-1

Metronidazole CAS#443-48-1

Basic Information

Effective Anti-anaerobic Activity:Metronidazole has strong bactericidal effects against a wide range of anaerobic microorganisms.


Dual-action Mechanism:Both the drug and its metabolites inhibit bacterial DNA synthesis, effectively stopping bacterial growth and reproduction.


Clinically Proven Efficacy:Recognized by the World Health Organization as a key treatment for anaerobic infections with significant therapeutic results.


Broad Therapeutic Applications:Widely used for the prevention and treatment of various infections, including oral, respiratory, gastrointestinal, abdominal, skin, and systemic infections caused by anaerobic bacteri.

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Product Description of Metronidazole CAS#443-48-1

Metronidazole is a nitroimidazole antibiotic active against anaerobic bacteria and Giardia, working by inhibiting bacterial DNA synthesis after metabolic activation. Designated by WHO in 1978 as the drug of choice for anaerobic infections, it was first used for vaginal trichomoniasis and is now widely applied to prevent and treat anaerobic infections throughout the body.


Product Application of Metronidazole CAS#443-48-1

This product has been used since 1959 for the treatment of vaginal trichomoniasis, and since 1970 for intestinal and extraintestinal amoebiasis. It is characterized by high efficacy, low toxicity, and a broad range of applications. However, animal studies have shown potential mutagenic and teratogenic effects.

Metronidazole exhibits strong antibacterial activity against most anaerobic bacteria. It is widely used in the treatment of amoebiasis, trichomoniasis, and various anaerobic infections.


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Product Information

Parameters


Melting point159-161 °C (lit.)
Boiling point301.12°C (rough estimate)
density1.3994 (rough estimate)
refractive index1.5800 (estimate)
Fp9℃
storage temp.2-8°C
solubilityacetic acid: 0.1 M, clear, faintly yellow
formcrystalline
pkapKa 2.62(H2O,t =25±0.2,Iundefined) (Uncertain)
colorwhite to light yellow
Water Solubility<0.1 g/100 mL at 20 ºC
Merck146157
BRN611683
BCS Class1,3
Stability:Stable. Incompatible with strong oxidizing agents.
InChIKeyVAOCPAMSLUNLGC-UHFFFAOYSA-N
LogP-0.02
IARC2B (Vol. 13, Sup 7) 1987
NIST Chemistry ReferenceMetronidazole(443-48-1)
EPA Substance Registry SystemMetronidazole (443-48-1)
Hazard CodesXn
Risk Statements40-46-45-39/23/24/25-23/24/25-11
Safety Statements36/37-45-53-16-7
WGK Germany3
RTECSNI5600000
F8
HS Code29332990
Hazardous Substances Data443-48-1(Hazardous Substances Data)


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FAQ

1. What kind of company is Bohai New Materials?
Bohai New Materials (Tianjin) Co., Ltd. is a foreign trade company specializing in the international trade of chemical products, located in the Binhai New Area of ​​Tianjin. Leveraging the strategic location of Tianjin Port, the company provides one-stop procurement and export services to global clients for a wide range of products, including plastic resins, basic chemical raw materials, fine chemicals, chemical fiber raw materials, and inorganic chemicals.


2. Which markets does the company serve?
Our products are primarily exported to Southeast Asia (Vietnam, Thailand, Indonesia, Malaysia), the Middle East (UAE, Saudi Arabia), Africa (Nigeria, Kenya), as well as Europe and the Americas.


3. Does the company have the qualifications to export hazardous chemicals?
Yes. We hold a valid license for the operation of hazardous chemicals and are well-versed in the export declaration, packaging, documentation, and transportation requirements for various types of hazardous goods. We are capable of handling the export of Class 3, Class 5, Class 8, and Class 9 hazardous chemicals.


4. What are the company's main products?
Our core product portfolio includes:
Plastic resins: PP, PE, PVC, ABS, PC, POM, etc.
Basic chemical raw materials: Soda ash, caustic soda, titanium dioxide, methanol, styrene, ethylene glycol, PTA, etc.
Fine chemicals: Pharmaceutical intermediates, pesticide intermediates, chemical additives, solvents, surfactants.
Chemical fiber raw materials: Polyester filament, polyester staple fiber, polyester chips (PET).
Inorganic chemicals: Calcium carbonate, talc powder, sodium sulfate, calcium chloride, magnesium chloride, etc.
Others: Paraffin wax, white oil, petroleum jelly (Vaseline), rubber, water treatment chemicals, etc.
If you have specific product requirements, please feel free to contact us; we will quickly source high-quality products to meet your needs.


5. How can I obtain a product quote? What information is required?
You can contact us via our official website, by phone, or by email. To ensure a quick and accurate quote, please provide the following details: product name and specifications, target purchase quantity, destination port, and desired delivery time. Please also inform us of any special packaging or testing requirements.

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